MCQ in Biopharmaceutics and pharmacokinetics BP604 T (Drugs Excretion MCQ) Quiz – 1

 

MCQ in Biopharmaceutics & Pharmacokinetics 

BP604 T (Drugs Excretion) 

Quiz – 1

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS

1. Which one of the following is the principal organ for drug excretion?

  A) Lungs 
B) Liver
C) Kidneys
D) Sweat glands

... Answer is : C) Kidneys

2. Compounds excreted in bile is classified into 3 categories. Which one of the following does not come under the categories?

A) Drugs with bile/plasma concentration ratio of less than 1
B) Drugs with bile/plasma concentration ratio approximately 1
C) Drugs with bile/plasma concentration ratio between 10-1000
D) Drugs with bile/plasma concentration ratio above 1000

... Answer is : D) Drugs with bile/plasma concentration ratio above 1000

3. What is the equation for biliary clearance?

A) No such equation is there
B) Plasma drug concentration / biliary excretion rate
C) Biliary excretion rate/ plasma drug concentration
D) Plasma drug concentration / Bile flow * biliary drug concentration

... Answer is : C) Biliary excretion rate/ plasma drug concentration

4. Which compounds are excreted through the lungs?

A) Gaseous
B) Lipophilic
C) Solid less than 100 Dalton
D) Liquid and hydrophilic

... Answer is : A) Gaseous

5. What is the mechanism of drug excretion for skin excretion?

A) Active secretion
B) Passive diffusion
C) Glomerular secretion
D) Passive reabsorption

... Answer is : B) Passive diffusion

6. Which of the following is not a factor influencing pulmonary excretion?.

A) Heart rate
B) Rate of respiration
C) Pulmonary blood flow
D) The solubility of volatile substance

... Answer is : A) Heart rate

7. What is the driving force for glomerular filtration?

A) Hydrostatic pressure of blood flow
B) High amount of aqueous pores
C) Hydrostatic pressure of plasma
D) Concentration gradient

... Answer is : A) Hydrostatic pressure of blood flow

8. What is total systemic clearance?

A) Sum of clearance from kidney
B) Sum of clearance from kidney and liver
C) Sum of renal and non-renal clearances
D) Sum of clearance form non-renal clearances

... Answer is : C) Sum of renal and non-renal clearances

9. What will be the elimination rate if the clearance is 130ml/min and drug concentration is 0.8 g/ml?

A) 100g/min
B) 104g/min
C) 130g/min
D) 140g/min

... Answer is : B) 104g/min

10. How do you calculate the rate of excretion by kidneys?

A) Rate of filtration + rate of secretion + Rate of absorption
B) Rate of filtration – the rate of secretion – Rate of absorption
C) Rate of filtration + rate of secretion – Rate of absorption
D) Rate of filtration – the rate of secretion + Rate of absorption

... Answer is : C) Rate of filtration + rate of secretion – Rate of absorption