MCQ in Biopharmaceutics and pharmacokinetics BP604 T ( Pharmacokinetics and Compartment model MCQ ) Quiz – 1

 

MCQ in Biopharmaceutics & Pharmacokinetics 

BP604 T (Pharmacokinetics and Compartment model MCQ) 

Quiz – 1

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS

1. Which of the following is not a mechanism for pharmacokinetic analysis?

  A) Human model 
B) Physiologic modeling
C) Compartment analysis
D) Non compartment analysis

... Answer is : A) Human model

2. In which of the model peripheral compartments are connected to a central compartment?

A) Caternary model
B) Physiologic model
C) Mammillary model
D) Compartment model

... Answer is : C) Mammillary model

3. In which model compartments are joined in series?

A) Compartment model
B) Physiologic model
C) Caternary model
D) Mammillary model

... Answer is : C) Caternary model

4. In noncompartmental analysis, Mean residence time is equal to _____________

A) 1/ Area under the zero moment curve
B) 1 / Area under the first-moment curve
C) The area under the zero moment’s curve/area under the first moment curve
D) The area under the first moment curve/area under the zero moment curve

... Answer is : D) The area under the first moment curve/area under the zero moment curve

5. Which of the following will be a disadvantage for the physiologic model?

A) Correlation of data in several animal species
B) Obtaining experimental data for each of the organs
C) Prediction of drug concentration in various body regions
D) The model gives an exact description of the drug concentration-time profile for any organ

... Answer is : B) Obtaining experimental data for each of the organs

6. What does the word “open” mean in the one compartment open model?.

A) Easy absorption
B) The drug easily enters
C) Unidirectional input and output
D) The drug readily mixes with the blood

... Answer is : C) Unidirectional input and output

7. Which of the following is not a factor of renal excretion?

A) Urine pH
B) Blood pH
C) Disease state
D) Blood flow to the kidneys

... Answer is : B) Blood pH

8. In the equation log C = log Co – KEt/2.303, what does Co stand for _______

A) Plasma drug concentration immediately after i.v. injection
B) Plasma drug concentration after 60 min of i.v. injection
C) Plasma drug concentration after 15 min of i.v. injection
D) Plasma drug concentration after 30 min of i.v. injection

... Answer is : A) Plasma drug concentration immediately after i.v. injection

9. Which drugs cannot be filtered through glomerulus?

A) Unbound
B) Free drug
C) Drugs bound to plasma proteins
D) Below molecular weight of 300 Dalton

... Answer is : C) Drugs bound to plasma proteins

10. What is the equation to find out the apparent volume of distribution?

A) 1 / plasma drug concentration
B) 1 / Amount of drug in the body
C) Plasma drug concentration/amount of drug in the body
D) Amount of drug in the body/plasma drug concentration

... Answer is : D) Amount of drug in the body/plasma drug concentration