MCQ in Biopharmaceutics and pharmacokinetics BP604 T (Plasma and Tissue Protein Drug Binding MCQ) Quiz – 1

 

MCQ in Biopharmaceutics & Pharmacokinetics 

BP604 T (Plasma and Tissue Protein Drug Binding) 

Quiz – 1

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS

1. What is the name of the drug binding site I of HSA?

  A) Diazepam binding site 
B) Tamoxifen binding site
C) Digitoxin binding site
D) Warfarin and azapropazone binding site

... Answer is : D) Warfarin and azapropazone binding site

2. Which of the given drugs bind to Α1 globulin?

A) Vitamins A, D, E, K
B) Ferrous ions
C) Carotenoids
D) Steroidal drugs

... Answer is : D) Steroidal drugs

3. Which of the given drugs bind to Β2 globulin?

A) Carotenoids
B) Ferrous ions
C) Steroidal drugs
D) Vitamins A, D, E, K

... Answer is : A) Carotenoids

4. Which drugs bind to RBC membrane?

A) Phenytoin
B) Imipramine
C) Acetazolamide
D) Pentobarbital

... Answer is : B) Imipramine

5. What reasons make tissue-drug binding important for drug distribution?

A) Increases the volume of distribution of drugs
B) Results in localization of drugs at a tissue specific site
C) Increases in absorption from the tissue due to concentration increasing
D) Increases the volume of distribution of drugs and results in localization of drug at a specific site

... Answer is : D) Increases the volume of distribution of drugs and results in localization of drug at a specific site

6. What is the relation between halogenated hydrocarbon and liver?.

A) Halogenated hydrocarbon is nutrition for liver
B) Halogenated hydrocarbon causes hepatotoxicity
C) Halogenated hydrocarbon is a drug for liver problems
D) Halogenated hydrocarbon forms the bile juices in liver

... Answer is : B) Halogenated hydrocarbon causes hepatotoxicity

7. Which metals get accumulated in the kidney?

A) Mercury, cadmium, iron
B) Mercury, lanthanum, lead
C) Mercury, cadmium, lead
D) Mercury, cadmium, fluoride ions

... Answer is : C) Mercury, cadmium, lead

8. Which one of the following factor related to protein-drug binding is not related to drug interactions with the binding site?

A) Inter subject variation
B) Allosteric changes in a protein molecule
C) Competition between the drug and the binding site
D) Competition between drugs and normal body constituents

... Answer is : A) Inter subject variation

9. Which drugs bind to HSA easily?

A) Neutral drug
B) Anionic drug
C) Cationic drug
D) Lipophilic drug

... Answer is : B) Anionic drug

10. Which drug easily bind to AAG?

A) Anionic drug
B) Neutral drug
C) Cationic drug
D) Lipophilic drug

... Answer is : C) Cationic drug