MCQ in Biopharmaceutics and pharmacokinetics BP604 T (Bioavailability and Bioequivalence) Quiz – 1

 

MCQ in Biopharmaceutics & Pharmacokinetics 

BP604 T (Bioavailability and Bioequivalence) 

Quiz – 1

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI 

AS PER PCI SYLLABUS

1. What is bioavailability?

  A) The time of absorption of the drug from its dosage form  
B) The rate of absorption of the drug from its dosage form
C) The time of absorption of the unchanged drug from its dosage form
D) The rate of absorption of the unchanged drug from its dosage form

... Answer is : D) The rate of absorption of the unchanged drug from its dosage form

2. What is the equation of bioavailable fraction?

A) 1/Administered dose
B) 1/Bioavailable dose
C) Administered dose/Bioavailable dose
D) Bioavailable dose/Administered dose

... Answer is : D) Bioavailable dose/Administered dose

3. Which of the following is not an objective of bioavailability studies?

A) Control the quantity of the drug to be administered
B) Development of new formulations of the existing drugs
C) Primary stages of development of suitable dosage form for new drug
D) Determination of the influence of excipients, patient-related factors, etc

... Answer is : A) Control the quantity of the drug to be administered

4. Which of the following is the pharmacodynamics method of studying bioavailability?

A) Stool excretion studies
B) Acute pharmacologic response
C) Plasma-level time studies
D) Urinary excretion studies

... Answer is : B) Acute pharmacologic response

5. Which of the following is not an important parameter of plasma level time studies?

A) Tax
B) Cmax
C) Steady state level
D) The area under the plasma level-time curve

... Answer is : C) Steady state level

6. What is the equation for bioavailability? .

A) [AUC]test Dstd τtest / [AUC]std Dtest τstd
B) [AUC]std Dstd τtest / [AUC]test Dtest τstd
C) [AUC]test Dtest τstd / [AUC]std Dstd τtest
D) 1 / [AUC]std Dtest τstd

... Answer is : A) [AUC]test Dstd τtest / [AUC]std Dtest τstd

7. Which of the following will not be a parameter that should be examined for urinary excretion data?

A) (dXu/dt)max
B) (tu)max
C) Xu
D) Cmax

... Answer is : D) Cmax

8. Which of the following is not measured in acute pharmacological response study?

A) Serum drug level
B) Pupil diameter
C) EEG
D) ECG

... Answer is : A) Serum drug level

9. What is bioequivalence?

A) Comparison between drugs to another drug
B) Comparison between 3-year-old drugs to the same new drug
C) Comparison between two or 3 characteristics of a drug to the same characteristics of a different drug
D) Comparison between a drug’s specific characteristics to a defined set of standards

... Answer is : D) Comparison between a drug’s specific characteristics to a defined set of standards

10. What is the chemical equivalence?

A) Two or more drug products contain the same labeled chemical substance in different quantity
B) Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
C) Two or more drug products contain the same labeled chemical substance in the same amount
D) Two or more drug products contain different labeled chemical substance giving the same therapeutic effect

... Answer is : C) Two or more drug products contain the same labeled chemical substance in the same amount