MCQ in Biopharmaceutics & Pharmacokinetics 

BP604 T (Plasma and Tissue Protein Drug Binding) 

Quiz – 2

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS








1. Which of the following is a correct method to find the fraction of unbound drug in plasma? Given where Cu is the concentration of unbound drug and C is total plasma drug concentration.
      A) Cu/C


... Answer is : A) Cu/C


2. Binding of drugs falls into 2 components those are _______________




... Answer is : D) Binding of drugs to blood components and to extravascular tissue

3. Which vitamin molecules will bind to alpha 2 globulin?





... Answer is : A) Vitamin A, D, E, K

4. HSA comes under which protein family?




... Answer is : C) Globulin


5. Which one of the below does not belong to the 4 classes of lipoprotein?




... Answer is : A) Fatty acids

6. What is the name of the drug binding site IV of HSA? .




... Answer is : C) Tamoxifen binding site

7. What is the name of the drug binding site III of HSA?




... Answer is : D) Digitoxin binding site

8. What is the name of the drug binding site II of HSA?





... Answer is : B) Diazepam binding site


9. Following is the order in decreasing order of drug binding to the extravascular tissue. Which one is the correct order?





... Answer is : A) Liver > kidney > lung > muscle

10. Which drugs accumulate in liver?




... Answer is : C) Basic drugs like imipramine