MCQ in Biopharmaceutics and pharmacokinetics BP604 T ( Pharmacokinetics and Compartment model MCQ ) Quiz – 2

 

MCQ in Biopharmaceutics & Pharmacokinetics 

BP604 T (Pharmacokinetics and Compartment model MCQ) 

Quiz – 2

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS

1. What is the equation to find out hepatic clearance?

  A) 1 / rate of elimination by the kidney 
B) 1 / plasma drug concentration
C) Plasma drug concentration/rate of elimination by the kidney
D) Rate of elimination by kidney/plasma drug concentration

... Answer is : D) Rate of elimination by kidney/plasma drug concentration

2. Which organ comprises the peripheral compartment in a two compartment model?

A) Muscles
B) Kidneys
C) Lungs
D) Liver

... Answer is : A) Muscles

3. In which of the following models the body is considered to be composed of several compartments?

A) Noncompartment model
B) Compartment model
C) Physiologic model
D) Human model

... Answer is : B) Compartment model

4. Which organs will make up the peripheral compartment?

A) Pancreas
B) Kidneys
C) Lungs
D) Liver

... Answer is : A) Pancreas

5. Which of the following is not a characteristic of the caternary compartment model?

A) Useful in predicting drug
B) It shows how many rate constants are necessary
C) It gives a visual representation of various rate processes in drug disposition
D) Compartments and parameters bear a relationship with physiologic functions

... Answer is : D) Compartments and parameters bear a relationship with physiologic functions

6. Which pharmacokinetic model is drawn on the basis of anatomic and physiologic data?.

A) Caternary model
B) Physiologic model
C) Mammillary model
D) Compartment model

... Answer is : B) Physiologic model

7. Which model is also known as membrane permeation rate limited?

A) Mammillary model
B) Compartment model
C) Physiologic model
D) Noncompartment model

... Answer is : C) Physiologic model

8. How much time does an intravenously administered drug take to complete a complete circulation?

A) 1 min
B) 1-3 min
C) 5-8 min
D) 7-10 min

... Answer is : B) 1-3 min

9. The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?

A) 625 l
B) 625 ml
C) 0.0016 mg/ml
D) 625 mg/ml

... Answer is : B) 625 ml

10. Which organs comprise the central compartment in a two compartment model?

A) Adipose
B) Muscles
C) Liver
D) Skin

... Answer is : C) Liver