MCQ in Biopharmaceutics & Pharmacokinetics 

BP604 T (Drugs Excretion) 

Quiz – 2

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS








1. Which of the following is not a physicochemical factor of drug that can affect the renal excretion?
      A) Lipid solubility


... Answer is : D) Disintegration rate


2. Which one is the correct equation to calculate the fraction of unbound drug in plasma?




... Answer is : D) Concentration of unbound drug in plasma / total plasma concentration of drug

3. What is the molecular weight cut off for biliary excretion?





... Answer is : C) More than 300 Dalton

4. For a certain drug, the bile flow rate is 0.7 ml/mm, the biliary drug concentration is 2g/ml and the plasma drug concentration is 0.8g/ml. What will be the bile clearance?




... Answer is : B) 1.75 ml/mm


5. What is the pH of the milk secreted by human mothers?




... Answer is : C) 6.4-7.6

6. What is the mechanism of drug excretion for biliary excretion?.




... Answer is : B) Active secretion

7. How is renal clearance expressed mathematically?




... Answer is : D) Rate of urinary excretion/plasma drug concentration

8. Which of the following compounds are used as agents to determine Glomerular Filtration Rate?





... Answer is : B) Creatinine


9. What is the equation for clearance?





... Answer is : D) Elimination rate / plasma drug concentration

10. How renal clearance ratio is expressed?




... Answer is : A) Renal clearance of creatinine / renal clearance of the drug