MCQ in Biopharmaceutics and pharmacokinetics BP604 T (Distribution) Quiz – 2

 

 

MCQ in Biopharmaceutics and pharmacokinetics 

BP604 T (Distribution) Quiz – 2

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS

1. What is the perfusion rate?

  A) The volume of tissue that flows per unit time per unit area of a blood vessel 
B) The volume of blood that flows per unit time per unit volume of tissue
C) The volume of blood that flows through the heart per unit time
D) The total volume of blood

... Answer is : B) The volume of blood that flows per unit time per unit volume of tissue

2. Who has more intracellular and extracellular water more in their body?

A) Aged
B) Infants
C) Children at puberty
D) Adults Of age more than 20

... Answer is : B) Infants

3. Who has higher fat content?

A) Children at puberty
B) Infants and elders
C) Adults of age above 70
D) Adults of age more than 20

... Answer is : B) Infants and elders

4. Who has poorly developed BBB?

A) Adults Of age more than 20
B) Children at puberty
C) Aged
D) Infants

... Answer is : D) Infants

5. During pregnancy, drug distribution is more. Which of the following sentences describe the given fact better?

A) The growth of the uterus, placenta, and foetus increases the volume thus increasing distribution. And even the baby forms a separate compartment for a drug to get distributed
B) The surface area increases in the mother’s body due to the presence of uterus, placenta, and foetus. Thus more area for distribution of drugs
C) The mother needs more drug due to high metabolism
D) The baby needs more drug

... Answer is : A) The growth of the uterus, placenta, and foetus increases the volume thus increasing distribution. And even the baby forms a separate compartment for a drug to get

6. What happens when an obese person is given with a lipophilic drug?.

A) A large amount of drug is needed as the person’s weight is more
B) High adipose tissue take up most of the lipophilic drug
C) He cannot absorb lipophilic drugs
D) Drug aggregation will begin

... Answer is : B) High adipose tissue take up most of the lipophilic drug

7. What is the consequence of diet high in fats?

A) The patient can’t be given with acidic drugs
B) The patient can’t be given with basic drugs
C) The high fatty acid level affect the binding of acidic drugs
D) The basic drugs will aggregate and become poisonous for him

... Answer is : C) The high fatty acid level affect the binding of acidic drugs

8. The extent to which a drug is distributed is a tissue depends upon ___________ and _____________

A) Tissue volume, tissue/blood partition coefficient of drug
B) Tissue surface area, tissue/blood partition coefficient of drug
C) The concentration of a drug, tissue/blood partition coefficient of drug
D) Blood density upon the tissue, tissue/blood partition coefficient of drug

... Answer is : A) Tissue volume, tissue/blood partition coefficient of drug

9. Which one of the following has a high perfusion rate?

A) Lungs and kidney
B) Muscle and skin
C) Bone
D) Fat

... Answer is : A) Lungs and kidney

10. Which one of the following has very low perfusion rate?

A) Liver and Heart
B) Fat and bone
C) Muscle and skin
D) Lungs and kidney

... Answer is : B) Fat and bone