MCQ in Biopharmaceutics and pharmacokinetics BP604 T (Absorption) Quiz – 2

MCQ in Biopharmaceutics and pharmacokinetics 

BP604 T (Absorption) Quiz – 2

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS 

1. Which one of these does not come under a physicochemical property of drugs?

  A) Drug solubility 
B) Dissolution rate
C) Drug stability
D) Disintegration time

... Answer is : D) Disintegration time

2. Which one is the correct sequence for drug absorption through the oral route?

A) Disintegration – Deaggregation – Absorption – Dissolution
B) Disintegration – Deaggregation – Dissolution – Absorption
C) Disintegration – Dissolution – Deaggregation – Absorption
D) Absorption – Dissolution – Disintegration – Deaggregation

... Answer is : B) Disintegration – Deaggregation – Dissolution – Absorption

3. The rate at which drug reaches the systemic circulation is determined by the slowest of the various steps involved in the sequence. This is known as ____________

A) Dissolution time
B) Gastric Emptying time
C) Disintegration time
D) Rate limiting step

... Answer is : D) Rate limiting step

4. Which sentence will define the Dissolution rate?

A) Amount of solid substrate that goes into solution under constant time under standard temperature, pH, solvent composition and constant surface area
B) Amount of solid substrate that goes into solution under constant time under standard temperature, pH, and pressure
C) Amount of solid substrate that goes into solution under constant time under standard temperature
D) Amount of solid substrate that goes into solution under constant time

... Answer is : A) Amount of solid substrate that goes into solution under constant time under standard temperature, pH, solvent composition and constant surface area

5. Which one of these is not a theory of Drug dissolution?

A) Interfacial barrier model
B) Diffusion layer model
C) Fick’s law of diffusion
D) Penetration or surface renewal theory

... Answer is : C) Fick’s law of diffusion

6. In the equation G=Ki (Cs-Cb), what does G stands for______________.

A) Effective interfacial transport constant
B) Concentration of the impurity
C) Dissolution rate per unit area
D) Concentration of the solute

... Answer is : C) Dissolution rate per unit area

7. What does the interfacial barrier model states?

A) Turbulence in the dissolution medium exists at the solid/liquid interface
B) Formation a thin film or layer at the solid-liquid interface
C) Solutes passes easily through the interfaces
D) An intermediate concentration exists at the interface

... Answer is : D) An intermediate concentration exists at the interface

8. Which form of drug formulation has disintegration time?

A) Syrups
B) Injections
C) Only tablets
D) Capsules and Tablets

... Answer is : D) Capsules and Tablets

9. What is the function of a granulating agent in drug formulation?

A) Used as solubilizer
B) Promote cohesive compacts
C) Tablets can disintegrate easily
D) Added if the required dosage is inadequate so that necessary bulk can be produced

... Answer is : A) Used as solubilizer

10. Which part of the membrane is responsible for the relative impermeability of polar molecules in and out of the cell?

A) Hydrophobic head
B) Hydrophobic core
C) Non polar head
D) Polar head

... Answer is : B) Hydrophobic core