MCQ in Biopharmaceutics and pharmacokinetics BP604 T (Absorption) Quiz – 4

 

MCQ in Biopharmaceutics and pharmacokinetics 

BP604 T (Absorption) Quiz – 4

MULTIPLE CHOICE QUESTIONS

Third Yr. B.PHARM  SEM-VI

AS PER PCI SYLLABUS

1. In the sequence of events in the drug absorption from orally administered solid dosage, which one comes at first?

  A) Disaggregation 
B) Dissolution
C) Disintegration
D) Absorption

... Answer is : C) Disintegration

2. Patient-related factors of drug absorption do not deal with which one of these?

A) Pharmaceutic ingredients
B) Intestinal transit time
C) Gastric Emptying time
D) Age

... Answer is : A) Pharmaceutic ingredients

3. Which one of the following is a critical rate-limiting step of drug absorption?

A) Size of the drug
B) Rate of dissolution
C) Size of the porous particle
D) Rate of drug disintegration

... Answer is : B) Rate of dissolution

4. What should be the ideal solubility rate of an orally administered drug in the pH range of 2 to 8?

A) 1-2 mg/ml
B) 3-4mg/ml
C) 4-6 mg/ml
D) 7-8 mg/ml

... Answer is : A) 1-2 mg/ml

5. Which theory takes into account that a thin film is created by the solution of the solid at the solid-liquid interface?

A) Danckwert’s model
B) Diffusion layer model
C) Interfacial barrier model
D) Penetration or surface renewal theory

... Answer is : B) Diffusion layer model

6. Which model does not approve the existence of the stagnant layer in the solid-liquid interface?.

A) Diffusion layer mode
B) Penetration or surface renewal theory
C) Danckwert’s model
D) Interfacial barrier model

... Answer is : C) Danckwert’s model

7. Which are the two rate-determining step of drug absorption when given orally?

A) Disintegration and Dissolution
B) Disintegration and deaggregation
C) Permeation through the membrane and Disintegration
D) Dissolution and permeation through the membrane

... Answer is : D) Dissolution and permeation through the membrane

8. Which tablets have longer Disintegration time?

A) Capsules
B) Sugar-coated tablets
C) Single coated tablets
D) Uncoated tablets

... Answer is : B) Sugar-coated tablets

9. Which is the other name of “cell eating”?

A) Endocytosis
B) Transcytosis
C) Phagocytosis
D) Pinocytosis

... Answer is : C) Phagocytosis

10. What is the major difference between Facilitated diffusion and Passive diffusion?

A) Inhibition by metabolic poisons
B) Energy is used
C) Downhill transport
D) Carrier-mediated transport

... Answer is :