Multiple choice questions                                                                                              





1. What are the characteristics of 2nd generation h1 receptor antagonists?

a) Selective for peripheral H1 receptors

b) Opposed to CNS H1 receptors

c) Selective for peripheral H1 receptors and opposed to CNS receptors

d) Selective to H1 receptors of CNS

 

2.  What is the chemical name of histamine

a)  2-(imidazole-3-yl) di-ethylamine

b) 4-Hydroxy-1-methylpeperidine

c) 2-(imidazole-4-yl) ethylamine

d) 2-(Dimethylamine ethyl chloride)

 

3.  H1 histamine receptors location.

a) bone marrow

b) parietal cells

c) Thymus

d) smooth muscles

 

4. Which of the following histamine receptor are responsible for regulation of gastric acid secretion.

a) H1- histamine receptor

b) H2- histamine receptor

c) H3- histamine receptor

d) H4- histamine receptor

 

5. Vasodilation and broncho-constriction occur due to the following histamine receptor.

a) H1- histamine receptor

b) H2- histamine receptor

c) H3- histamine receptor

d) H4- histamine receptor


6. Which of the following drug is Piperazine derivative.

a) Astemizole

b) Promethazine

c) Cetrizine

d) Loratadine

 

 7.  Which of the following is the first antihistamine?

a) Piperoxan

b) Ethylenediamine

c) Alkylamines

d) Tricyclics


8.  Which of the following histamine receptor increase permeability during inflammation reaction?

a) H1 receptor

b) H2 receptor

c) H3 receptor

d) H4 receptor


9.  Antihistamine drugs are antagonists for which receptor?

a) H1 receptor antagonist

b) H2 receptor antagonist

c) H3 receptor antagonist

d) H4 receptor antagonist

10.  which of the following anti-histamine drug is ethylenediamine derivatives

a) Pyrilamine

 b)Diphenhydramine

 c)Doxylamine

 d)Pheniramine

 

11. which of the following drug is Narcotic Agonist-Antagonist in nature

 a) Naloxone

 b) Nalorphine

 c) Naltrexone

 d)Nalmefene

 

 12.  which of the following anti-histamine drug is Propylamine analogue.

 a) Triprolidine

 b)Diphenhydramine

 c) cyclizine

 d)Chlorpheniramine

 

13. What is the major side effect of first generation H1 antagonist.

 a) Vomiting

 b) Induce sedation

 c) Motion sickness

 d) Nausea

 

14. which of the following is opioid receptor.

 a) kappa

 b) beta

 c)alpha 1

 d) beta 3

 

15. What are opioid analgesics?

a) Render a specific portion of the body insensitive to pain

b) Render the full body of the patient insensitive to pain

c) Render insensitive to pain by binding to opioid receptors

d) Render a specific CNS of the body insensitive to pain

16. Which of the following are natural opiates?

 a) Morphine

b) Oxycodone

c) Fentanyl

d) Endomorphins

 

17. Which of the following are semi-synthetic opiates?

a) Codeine

b) Hydromorphone

c) Fentanyl

d) Endomorphins


18. Which of the following are fully synthetic opioids?

a) Codeine

b) Oxycodone

c) Methadone

d) Endomorphins

 

19. Which of the following are endogenous opioid peptides?

a) Codeine

b) Oxycodone

c) Fentanyl

d) Endomorphins

 

20. How does the general opioids function?

a) Render a specific portion of the body insensitive to pain

b) Render the full body of the patient insensitive to pain

c) Render insensitive to pain by decreasing the pain threshold

d) Render a specific CNS of the body insensitive to pain

 

21. Which of the following side effects of morphine is the most dangerous?

a) Excitation

b) Nausea

c) Constipation

d) Tolerance and dependence

 

22. What is opiophobia?

a) Fear of opioid plant

b) Fear of drugs

c) Fear of prescribing opioid drugs

d) Fear of anesthesia

 

23. Which of the following is the long term effect of heroine?

a) Dryness of mouth

b) Collapsed veins

c) Muscle weakness

d) Euphoria

 

24. What is the antagonist for heroin?

a) Naloxone

b) Oxycodone

c) Fentanyl

d) Endomorphins

 

25. Which of the following Fentanyl analogues is ultra-short acting analgesic?

a) Alfentanyl

b) Sufentanil

c) Remifentanil

d) Carfentanil

 

26. Which of the following fentanyl analogue is used in heart surgery?

a) Alfentanyl

b) Sufentanil

c) Remifentanil

d) Carfentanil

 

27. Which of the following is the shortest acting fentanyl analogue?

a) Alfentanyl

b) Sufentanil

c) Remifentanil

d) Carfentanil

 

28. Which of the following fentanyl analogue is being used in veterinary practice?

a) Alfentanyl

b) Sufentanil

c) Remifentanil

d) Carfentanil

1. c

2. c

3. d

4. b

5. a

6. c

7. a

8. a

9. a

10. a

11. b

12. d

13. b

14. a

15. c

16. a

17. b

18. c

19. d

20. c

21. d

22. c

23. b

24. a

25. a

26.b

27. c

28. d