MCQ on TLC (Thin Layer Chromatography)
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Multiple Choice Question with Answers on TLC
1. Which is not TLC
development ?
A. Sandwich method
B. Horizontal
C. Teo dimensional
D. Column
2. Which is not an
application of TLC ?
A.TLC can be successful used
for isolation of vitamin like A,D,andE using silica gel.
B. Identification of drug.
C. Neomycin sulphate can be
isolating on activated compound.
D. To determination of
moisture.
3. In Iodine chamber,
which colour spot are seen ?
A. Red colour.
B. Brown colour.
C. Yellow colour
D. Green colour
4. Half plate size is
A. 20×10 cm
B. 10× 10 cm
C. 20× 20 cm
D. 5×5 cm
5. Which method are
used for suspension spraying ?
A. Pouring
B. Dipping
C. Spraying
D. Spreading
6. Capillary diameter
is
A. 5 mm
B. 6 mm
C. 7 mm
D. 10 mm
7. Which temperature
is required for activation of plate ?
A. 110-120 C°
B. 120-130 C°
C. 130-149 C°
D. 150-160 C°
8. Which is not
Requirement of mobile phase?
A. It should be not toxic.
B. It should be easily
available.
C. It should be chemically
inert.
D. It should be chemically
active.
9. How many time is
required to dry TLC plate?
A. 15 minutes
B. 30 minutes
C. 10 minutes
D. 7 minutes
10. In quantitative
T.L.C radioactive material can be studied by (GATE 1997)
A. Visual
comparison
B. Gravimetry
C. Densitometer
D. Ginger
counter
11. The stationary
phase in thin layer chromatography is: - (Gate1993)
A. Liquid
held between glass
B. Glass
plate
C. Silica
gel
D. None
of the above
12. In
TLC, initially the sample is
A. In contact with mobile phase
B. Not
in contact with mobile phase
C. Coated at the level of mobile phase
D. Coated
below the level of mobile phase
13. What is the
principle of TLC ?
A. Partition
B. Absorption
C. Adsorption
D. A and B
14. Which sentence is
false about TLC ?
A. It is very sample method
B. It is less time consuming.
C. Applied to allow type of
sample.
D. It is very costly.
15. Which is not
factor for choosing adsorbent ?
A. Nature of the adsorbent
B. Solubility of the
adsorbent
C. Chemical nature
D. Temperature.
16. The m.p. is flow
by
A. Capillary action
B. Partition coefficient
C. Temperature
D. All of the above
17. The components
with more affinity towards the stationary phases is
A. Travels slow
B. Travels fast
C. A and B
D. None of the above
18.The components
with less affinity towards the stationary phases is
A. Travels slow
B. Travels fast
C. A and B
D. None of the above
19. Chromatography is a physical method
that is used to separate and analyse __________
A. Simple
mixtures
B. Complex
mixtures
C. Viscous
mixtures
D. Metals
20. In chromatography, the stationary
phase can be ___________ supported on a solid.
A. Solid
or liquid
B. Liquid
or gas
C. Solid
only
D. Liquid
only
21. In chromatography, which of the
following can the mobile phase be made of?
A. Solid
or liquid
B. Liquid
or gas
C. Gas
only
D. Liquid
only
22. Which of the following types of
chromatography involves the separation of substances in a mixture over a 0.2mm
thick layer of an adsorbent?
A. Gas
liquid
B. Column
C. Thin
layer
D. Paper
23. Chromatography cannot be used to
purify volatile substances.
A. True
B. False
24. Chromatography cannot be used to
separate delicate products.
A. True
B. False
25. In Thin layer chromatography, the
stationary phase is made of _________ and the mobile phase is made of _________
A. Solid,
liquid
B. Liquid,
liquid
C. Liquid,
gas
D. Solid,
gas
26. In which of the following type of
paper, chromatography does the mobile phase move horizontally over a circular
sheet of paper?
A. Ascending
paper chromatography
B. Descending
paper chromatography
C. Radial
paper chromatography
D. Ascending
– descending chromatography
27. A combination of paper chromatography and
electrophoresis involves
A. partition
chromatography
B. electrical
mobility of the ionic species
C. both
(1) and (2)
D. none
of these
28. Thin layer chromatography is
A. partition
chromatography
B. electrical
mobility of ionic species
C. adsorption
chromatography
D. none
of the above
1.
D |
2.
D |
3.
B |
4.
A |
5.
C |
6.A |
7.
B |
8.
D |
9.
B |
10.
D |
11.
C |
12.B |
13.C |
14.D |
15.
D |
16.
A |
17.
A |
18.B |
19.
B |
20.
A |
21.
B |
22.
C |
23.
B |
24.
B |
25.
A |
26.
C |
27.
C |
28.
C |
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