MCQ on  Column Chromatography


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Multiple choice question with answer

 

1. Silica gel used in most of adsorbent columns contains-OH group. So it is : (GATE 2005)

A.    Basic

B.     Neutral

C.     Acidic

D.    Both acidic and basic

 

2. Partition Chromatograph is known as : (NIPER M. PHARM 2004)

A.    Solid-liquid

B.     Gas-liquid

C.     Liquid-liquid

D.    None of these

3. In chromatographic separation the different species in the sample undergo the process of

(Gate 2008)

A.    Chemical interaction

B.     Partition

C.     Volatilization

D.    ionization

 

4. Which of the following types of chromatography involves the process, where mobile phase moves through the stationary phase by the influence of gravity or capillary action?

A.    Column Chromatography

B.     High Pressure Liquid Chromatography

C.     Gas Chromatography

D.    Planar Chromatography

 

5. Liquid chromatography can be performed in which of the following ways?

A.    Only in columns

B.     Only on plane surfaces

C.     Either in columns or on plane surfaces

D.    Neither in columns nor on plane surfaces

 

6. In Column chromatography, the stationary phase is made of _________ and the mobile phase is made of _________

A.    Solid, liquid

B.     Liquid, liquid

C.     Liquid, gas

D.    Solid, gas

 

7. Which of the following cannot be used as adsorbent in Column adsorption chromatography?

A.    Magnesium oxide

B.     Silica gel

C.     Activated alumina

D.    Potassium permanganate

 

8. In which type of chromatography, the stationary phase held in a narrow tube and the mobile phase is forced through it under pressure?

A.    Column chromatography

B.     Planar chromatography

C.     Liquid chromatography

D.    Gas chromatography

 

9. In column switching chromatography

A.    compounds trapped on one column are eluted to another column

B.     one column is removed and replaced by another

C.     the flow to the column is switched on and off repeatedly

D.    any of the above

 

10. Which of the following detectors give mass flow-dependent signals?

A.    Electron capture detector

B.     Field ionisation detector

C.     Thermal conductivity detector

D.    All of the above

 

11. Headspace analysis is carried out in order to

A.    analyse volatile compounds from solid or liquid samples

B.     determine the psychological state of the tutor

C.     analyse the column contents ahead of the sample

D.    determine non-volatiles

 

12. What does the retention factor, k', describe?

A.    The distribution of an analyte between the stationary and the mobile phase

B.     The migration rate of an analyte through a column

C.     The velocity of the mobile phase

D.    All of these

 

13.   The mobile phase in column chromatography acts as a

A.                Solvent for sample 

B.                 Developer and as eluent

C.                 As eluent only  

D.                Both (a) and (b)

 

14.   Silica gel 60 F254  contains

A.             Gypsum as binder

B.              Fluorescent indicator

C.              254 µm particle size

D.             Both (a) and (b)


1. C

2. C

3. B

4. D

5. C

6. A

7. D

8. A

9. A

10.  B

11. A

12. B

13. D

14. D




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