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QUESTION BANK OBJECTIVES 

MUILTIPLE CHOICE QUESTIONS

1. Adulteration means-

(A) confirmation of identity

(B) determination of purity

(C) debasement of an article

(D) confirmation and determination of purity & identity

 

2. Generally clove is adulterated with-

(A) mother clove

(C) clove stalks

(B) father clove

(D) mother clove and clove stalks

 

3. Medicinal ginger is generally adulterated with

(A) Japanese & African ginger

(B) American & Arabian ginger

 (C) Indian & Pakistani ginger

(D) None of the above

 

4. Drug evaluation means-

(A) confirmation of identity

 (B) determination of purity & quality

(D) substitution with inferior drugs

(C) debasement of an article

(A) A.C

(B) A,B

(C) B, C

(D)C, D

 

5. Which of the following is not the method of evaluation / standardization of crude drugs?

(A) Alphabetical

(B) Morpholgical

(D) Chemical

(C) Microscopical

 

6. In organoleptic evaluation the drugs are evaluated through-

(A) Chemical constituents

 (B) Therapeutic uses

(D) Gross morphology

(C) Histological characters

 

7. Which of the following is not the part of flower?

(A) Calyx

(B) Corolla

(C) Bark

(D) Gynoecium

 

8. Leaves are -

(A) modified shoot meant for production of seeds

(B) fertilized ovule

(C) flattened lateral outgrowth of stem

(D) matured ovary

 

9. Flowers are-

(A) modified shoot meant for production of seeds

(B) fertilized ovule

(C) matured ovary with or without associated parts

(D) flattened lateral outgrowth of stem

 

10. The bunch of flowers is called as-

(A) Corolla

 (B) Androecium

(C) Bark

(D) Inflorescence

 

11. Bark is collected from-

(A) Leaves

(C) Branches & trunk of trees

(B) Flowers

(D) Fruits

 

 

12. Which one of the following is not the common shape of bark?

 (A) Curved

(C) Recurved

(B) Crenate

(D) Quill

 

13. Which one of the following is not a type of margin of the leaf ?

 (A) Entire

(B) Serrate

(C) Double quill

(D) Sinuate

 

14. Fruits are-

(A) modified shoot meant for production of seeds

(B) fertilized ovule

(C) flattened lateral outgrowth of stem

(D) matured ovary with or without associated parts

 

15. Which of the following is not the character of seed ?

(A) Calyx

(C) Micropyle

(B) Hilum

(D) Raphe

 

16. Which one of the following is not the example of seed drug ?

(A) Nux vomica

(B) Aloe

(D)Castor

(C) Isapghulla

17. The taste of liquorice is-

(A) Bitter

(C) Acrid

(B) Sweet

(D) Pungent

 

18. Which of the following is not a type of trichome ?

(A) Glandular

(B) Cruciferous

(C) Non glandular

(D) Hydathodes

 

19. The main function of stomata is to -

(A) Exchange the gases

(B) Elongate the roots

(C) Prepare the food

(D) None of the above

 

20. Which is not a type of stomata ?

(A) Uniserate

(C) Gramineous

 (B) Moss

(D) Gymnospermous

 

21. Which of the following is not a dicotyledonous type of stomata ?

(A) Diacytic

(C) Anisocytic

(B) Moss

(D) Rubiaceous

 

22. In Caryophyllaceous or Diacytic type of stomata, the stoma is accompanied by two subsidiary cells, the long axes of which are-

(A) parallel to that of stoma

(C) at right angles to that of stoma

 (B) 45° to that of stoma

(D) none of the above

 

23. Rubiaceous or Paracytic type of stomata, the stoma has two subsidiary cells, the long axes of which are

(A) 45 to that of stoma

(B)  parallel to that of stoma

(C) at right angles o that of stoma

(D) none of the above

 

24. The stationary phase used in gel permeation chromatography is -  (GATE 2002)

(A) Alumina

(B) Squalene

(C) Charcoal

(D) Styrene divinyl benzyl copolymer

 

25 Palisade ratio is-

(A) total number of palisade cells beneath each upper epidermal cell

(B) total number of palisade cells beneath mesophyll

C) average number of palisade cells beneath each upper epidermal cell

(D) none of the above

 

26, Lycopodium spore method was developed by-

(A)James Rodrix

(B) Engler

(C) Linnaeus

(D) Wallis

 

27. 1mg of powdered lycopodium contains-

A) 94000 spores

(B) 74000 spores

(C) 84000 spores

(D) 64000 spores

 

28. Lycopodium powder method can be used to find out percentage purity of crude drugs

contain- (Gate: 2003)

 (A) multilayered tissue or cells

(B) well defined particles which can be counted

(C) oil bubbles

(D) characteristic particles of irregular thickness the length of which can be measured

 

29. The quantitative values determined for the identification of leaf drugs remain constant throught

the age of plant except-(Gate: 2005)

(A) Stomatal number

(C) Veinislet number

(B) Veinlet termination number

(D) Stomatal index

 

30. While performing the chemomicroscopy of a drug lignified trichomes were observed. Probable

drug is:-(GATE : 2006)

 (A) Lobelia

(B) Buchu

(c) Nux vomica

(D) Mint leaves

 

31. Cruciferous or Anisocytic type of stomata are found in:-

(A) Digitalis & Bearberry leaves

C) Belladonna & Datura leaves

(B) Senna & Coca leaves

(D) Mint leaves

 

32. Caryophyllaceous or Diacytic type of stomata are found in:-

 (B) Belladonna & Datura leaves

(A) Digitalis & Bearberry leaves

(C) Senna & Coca leaves

D)Thyme and spearmint leaves

 

33. The foreign organic matter in the fennel should be:-

 (A) not more than 2%

(B) not more than 4%

(C) not more than 1%

(D) not more than 3%

 

34. The moisture content of digitalis should be :-

A) not more than 8%

(B) not more than 5%

(C) not more than 1%

(D) not more than 11%

 

35. The moisture content of tragacanth should be-

 (A) not more than 5%

(C) not more than 15%

(B) not more than 10%

(D) not more than 20%

 

36.The melting point range of Hydrous wool fat is-

(A) 115 -120° C

(B) 45-50 C

(C) 34-40° C

(D)10-20° C

 

37. The viscosity of Newtonian liquids can be determined by-

(A)Capillary viscometer

(C) Sliding viscometer

(B) Rotating viscometer

(D) Polarimeter

 

 

38. The viscosity of Non- Newtonian liquids can be determined by-

(A)Capillary viscometer

(C) Sliding viscometer

(B) Rotating viscometer

(D) Polarimeter

 

39. The volatile oils are:-

(A) insoluble in alcohol and chloroform

(B) soluble in alcohol and chloroform

(C) soluble in water

(D) none of the above

 

40. Dextrorotatory (+) means:-

(A) rotation to left

(B) rotation to right

(C) rotation to downward

(D) none of the above

 

41. Levorotatory (-) means:-

(A) rotation to left

(C) rotation to right

(B) rotation to downward

(D) none of the above

 

42. Optical rotation is measured by:-

(A) Viscometer

(B) Opticometer

(C) Polarimeter

(D) Microtome

 

43. The volatile oil content of ajowan is:-

(A) not less than 3.5% v/w

(B) not less than 1% v/w

(C) not less than 0.3% v/w

(D) not less than 2% v/w

 

44. Total ash value in case of crude drug signifies :- (GATE 2003)

(A) organic content of the drug

(B) mineral matter in the drug

 (C) addition of extraneous matter such as sand, stone etc.

(D) woody matter present in the drug

(A) C, D

(B) B, C

(C) A, B

(D) A, D

 

45. One of the following parameter is not used in quality control of crude drugs :-

(A) Total ash

(B) Water soluble ash

(C) Acid insoluble ash

(D) Water insoluble ash

 

46. The acid insoluble ash is helpful in determining the :-

(A) excessive sand mixed with drug

(B) volatile oil content of drugs

(C) tannin content of drugs

(D) none of the above

 

47. The acid insoluble ash content of senna should be:-

(A) not more than 1% w/w

(B) not more than 3% w/w

 (C) not more than 2% w/w

(D) not more than 4% w/w

 

48. The total ash content of ginger should be:-

(A) not more than 4% w/w

(B) not more than 5% w/w

(D) not more than 7% w/w

(C) not more than 6% w/w

 

49. The total ash content of cinchona should be:-

(A) not more than 1% w/w

(C) not more than 3% w/W

(B) not more than 2% w/w

(D) not more than 4% w/w

 

50. One of the following parameter is not used in quality control of crude drugs

(A) water soluble extractive

(B) alcohol insoluble extractive

(C) alcohol soluble extractive

(D) ether soluble extractive

 

51. The non- volatile ether soluble extractive value represents-

(A) Fixed oils and resins

 (B) Volatile oil content

 (C) Sugars & glycosides

(D) None of the above

 

52. The principle of separation of thin layer chromatography is-

(A) Absorption

(B) Attraction

(C) Adsorption

(D) None of the above

 

53. R, means

(A) Reverse factor

(C) Rotation factor

(B) Rolling factor

(D) Retardation factor

 

54. HPTLC means

(A) High performance thin layer chromatography

(B) High pressure thin layer chromatography

(C) High partition thin layer chromatography

(D) None of the above

 

55. The principle of separation of HPTLC is :-

(A) Absorption

(C) Adsorption

(B) Attraction

(D) None of the above

 

56. The size of the sample spotted on HPTLC plate should not be more than-

(A) 0.1mm in diameter

 (B) 1mm in diameter

(C) 10mm in diameter

(D) 5mm in diameter

 

57. In column chromatography when stationary phase is liquid it is termed as:-

(A) Column partition chromatography

(B) Column adsorption chromatography

(C) Column - column chromatography

(D) None of the above

 

58. Gas chromatography was introduced by

(A) Hardy and Gerad in 1875

(B) James and Martin in 1952

(C) Posselt and Reiman in 1828

(D) Bentham and Hooker in 1883

 

59. The principle of separation in gas liquid chromatography is :-

(A) Adsorption

(B) Absorption

(C) Partition

(D) Attraction

 

60. The compounds to be analyzed by gas chromatography should be :-

(A) Non volatile

(B) Volatile

(C) Volatile and thermostable

(D) Non volatile and thermostable

 

61. Which of the following gaseous is not employed as mobile phase in gas liquid chromatography?

(A) Carbondioxide

(B) Hydrogen

(C) Helium

(D) Nitrogen

 

 

62. Which of the following is not used as detector in gas chromatography?

(A) Katharometer

(B) Flame ionization detector

(C) Nitrogen detector

(D) Electron capture detector

 

63. To overcome the problem of badly tailed peaks in gas chromatography, the technique used called as:

(A) Gel permeation

(B) Derivatisation

(C) PEEK

(D) None of the above

 

64. The spectral range of ultra-violet spectroscopy is :-

(A) 185-380nm

(B) 380-780nm

(C) 780-3000nm

(D) 3-40um

 

65. A The spectral range of infra red spectroscopy is

(A) 185-380nm

(C) 780-3000nm

(B) 380-780nm

(D) 3-40um

 

66. A Which one of the following is not a type of bioassay method.

(A) Toxic

(B) Symptomatic

(C) Titrimetric

(D) Tissue

 

67. Crude fibre value of a drug is a measure of : (GATE 2004)

(A) Soft tissue matter

(B) Mineral matter.

(C) Woody matter

(D) Organic matter

 

68. In gel permeation chromatography molecules are separated on the basis of their (GATE 1995)

(A) Chemical nature

(B) Adsorptive properties

(C) Size and shape

(D) Partition coefficient

 

69. Organoleptic evaluation includes,

(A) Impressions on organs of senses        

(B) Histological characters

(C) Chemical nature                                 

 (D) Pharmacological uses


70. The following is the test for Alkaloids

(A) Molischs test                                          

(B) Dragendroff’s test

(C) Libermann – Burchard test                   

 (D) Benedicts test

71. Qantiative microscopy is also known as

(A) Lycopodium spore method                        

(B) Stomatal method

(C) Phytochemical method                             

 (D) Water determination method


72. Karl fischer method is used in the determination of

(A) Moisture content                           

 (B) Ash content

(C) Bitterness content                        

  (D) Chemical content

 

73. Ash values of the  crude determines the

(A) Organic constituents               

(B) Inorganic constituents

(C) Cell constituents                     

(D) Chemical constituents


74. Heating a drug at 1050C in an oven to a constant weight is known as

(A) Volatile oil determination            

(B) Moisture content determination

(C) Melting point determination        

(D) Ash value determination


75. The residue remaining after incineration is called as

(A) Ash                                              

(B) Extract

(C) Waste material                 

(D) Foreign matter

76. Swelling Index is used to determine amount of  the following in the crude drugs

(A) Moisture                        

(B) Volatile oils

(C) Crude fibres                  

(D) Mucilage

77. Which of the following is under physiochemical evaluation except

(A) Ash value

(B) Moisture content

(C) Chromatographic finger print

(D) Bitterness value 


78. Herbal drug should be stored at

A.    Cool place

B.     Cool & dry place 

C.     Dry place

D.    Moist & cool place

 

79. Rf value will always be

A. Above 1

B. 0

C. Less than 1

D. Less than 0

 

80 .Crude drug is considered as one of pharmacopoeial quality, when:

(A) it meets both the general requirements of the pharmacopoeia and the requirements

     of the corresponding paragraph in the pharmacopoeia.

(B) it meets the requirements of the corresponding paragraph in the pharmacopoeia.

(C) it meets the requirements of the national Standard I.

(D) it meets the general requirements of the pharmacopoeia.

 

 81. Definition of crude drugs in the Pharmacopoeia:

(A) plant part used in medicine.

(B) plant part containing the highest content of the bioactive/characteristic compound/s.

(C) dried part of the medicinal plant.

(D) plant part or its preparations described in the paragraphs of the Pharmacopoeia.

 

82. In the estimation of arsenic which one of following reagent used

A.    N,N-diethyl methyl dithio-carbamate

B.     N,N-dimethyl ethyl dithio-carbamate

C.     N,N-diethyl methyl dichloro-carbamate

D.    N,N-dimethyl ethyl dichloro-carbamate


83. What is maximum limit of cadmium in crude drug and formulation?

A.    0.3 ppm  

B.     3 ppm 

C.     10 ppm

D.    1 ppm


84. 10 ppm is the limit for which heavy metals in crude drug and formulation

A.    Lead 

B.     Cadmium

C.     Arsenic

D.    Mercury


85. For identification of  E. Coli  limits in herbs and herbal formulation one of the selective medium used

A.    MacConkey broth    

B.     Tetrathionate bile brilliant green broth

C.     Soybean-casein digest medium

D.    Agar medium


86 . Standard for determination of bitterness value as per WHO guideline standard used is

A.    Gentiopicirin

B.     Sweretin

C.     Quinine

D.    Non of above


87 . Pesticide limit in in crude drug and formulation as per WHO is less than

A.    0.1ppm 

B.     1 ppm

C.     10 ppm 

D.    3 ppm

88. As per WHO guidelines for evaluation of tannin content one of the following reagent used


A.  A.   Hide powder

B.     B. Ferric chloride

C.     C. Ferrous sulphate

D.    D. Ninhydrine reagent


89. In determination the series of test tube which contain

A.    Minimum concentration, which produce form of 1cm height and stable for 30 min.

B.     Minimum concentration, which produce form of 1cm height and stable for 15 min.

C.     Minimum concentration, which produce form of 1cm height and stable for 1 min.

D.    Minimum concentration, which produce form of 1cm height and stable for 5min.


90. Following is not the physiochemical evaluation test for organized crude drug

A.    Swelling index

B.     Refractive index

C.     Foreign organic matter

D.    None of above


91. when two guard cells are surrounded by three subsidiary cells and one of which is smaller than rest of two is …

A.    Anisocytic stomata

B.     Actinocytic stomata

C.     Anomocytic stomata

D.    Diacytic stomata


92.____________ o C and above temperature used for in determination of moisture content

A. 55

B. 455

C. 105

D. 75

93. Palisade ratio is the average number of palisade cells present____________

A. In 1 mm square area of leaf

B. In 1 cm square area of leaf

C. under one epidermal cell

D. under ten epidermal cell

 

 

1.       C

2.       D

3.       A

4.       B

5.        A

6.       D

7.       C

8.       C

9.       A

10.   D

11.   C

12.   B

13.   C

14.   D

15.   A

16.   B

17.   B

18.   B

19.   A

20.   A

21.   B

22.   C

23.   B

24.   D

25.   C

26.   D

27.   A

28.   B

29.   D

30.   C

31.   C

32.   D

33.   A

34.   A

35.   C

36.   C

37.   A

38.   B

39.   B

40.   B

41.   A

42.   C

43.   D

44.   B

45.   D

46.   A

47.   C

48.   C

49.   D

50.   B

51.   A

52.   C

53.   D

54.   A

55.   C

56.   B

57.   A

58.   B

59.   C

60.   C

61.   A

62.   C

63.   B

64.   A

65.   D

66.   C

67.   C

68.   C

69.   A

70.   B

71.   A

72.   A

73.   B

74.   B

75.   A

76.   D

77.   D

78.   B

79.   C

80.   A

81.   D

82.   A

83.   A

84.   C

85.   A

86.   C

87.   B

88.   A

89.   B

90.   B

91.   B

92.   C

93.   C